How we’re exposed to an ingredient matters greatly in terms of our long-term health. 
  
Research shows that inhaling titanium dioxide particles in significant quantities over time can cause adverse health outcomes. Unless you work in an industrial setting, inhaling substantial amounts of titanium dioxide is highly unlikely. 

This precipitate is not suitable for a pigment until it is filtered, dried, crushed, heated to a high temperature and quenched in cold water. The second heating in a muffle furnace at 725 °C produces crystals of the right optical size.

In food, titanium dioxide has a few different uses. Most notably, its food-grade form is used as a colorant to enhance and brighten the color of white foods such as dairy products, candy, frosting, and the powder on donuts. For foods that are sensitive to UV light, titanium dioxide is used for food safety purposes to prevent spoilage and increase the shelf life of food.

Le lithopone, blanc de lithopone ou blanc de Comines est un pigment blanc composé d'un mélange de sulfure de zinc et de sulfate de baryum, généralement en proportions équimolaires.

But if thats not quite enough..............